Leading causes of death in Mexico 2025 INEGI statistics, Digi Mart USA News (Mexico): The Instituto Nacional de Estadística y Geografía (INEGI) has released its Statistics of Registered Deaths (EDR) report for 2025, offering a detailed picture of the diseases and causes that are claiming lives in the country.
During that period, 792,187 deaths were recorded nationwide, a crude rate of 606 deaths per 100,000 inhabitants. Although the total remains considerable, the figure shows a slight improvement compared with the previous year, with 27,485 fewer deaths than in 2024.
INEGI processed information from 4,846 official sources, including death certificates issued by Civil Registry offices and Forensic Medical Services, as well as death records and statistical notebooks provided by the Public Ministry. Of the total, 97.4 percent (771,178 cases) occurred during 2025, while the remaining 2.6 percent (21,009 deaths) were late registrations of events from earlier years.
The vast majority of deaths were linked to health deterioration. Some 89.9 percent of people died from illnesses and chronic or acute conditions, while 10.1 percent resulted from external causes, a category that mainly includes accidents, homicides and suicides.
The gender gap in mortality remains evident. Men accounted for 55.9 percent of deaths and women for 44 percent; in 556 cases (0.1 percent), the sex of the deceased could not be specified.
Mortality was not evenly distributed across the calendar year. The highest peak occurred early in the year: January led with 10.1 percent of total deaths, followed by March with 8.9 percent and May with 8.7 percent.
By place of usual residence, Chihuahua recorded the highest standardized rates in the country, with 786 registered deaths and 761 occurred deaths per 100,000 inhabitants. Quintana Roo and Sonora followed with high rates.
Southern states showed the lowest relative impact, with Campeche and Guerrero posting the lowest indicators in both standardized rates, below the national averages of 606 registered deaths and 590 registered and occurred deaths per 100,000 inhabitants.
The five leading causes of death in Mexico during 2025 were:
Heart diseases: The leading cause overall, with 183,141 deaths (98,588 men and 84,523 women), making it the greatest health threat for both sexes.
Diabetes mellitus: Ranked second with 109,839 deaths. Unlike heart disease, the gender gap was minimal, with 54,873 cases among men and 54,965 among women.
Malignant tumors (cancer): Caused 95,362 deaths. This category was the only one in the top three in which deaths among women (50,097) exceeded those among men (45,265).
Liver diseases: Held fourth place nationally with 39,277 recorded cases during the year.
Accidents: Completed the top five in fifth place, claiming 38,769 lives nationwide, closely behind liver-related deaths.
